Besides the lectures by our invited speakers who will talk about recent results in research regarding stress on molecular levels as well as in the field of neuroscience and psychology, there will be hands-on workshops and seminars provided by a number of research groups at the university of Marburg. In those workshops you will gain an insight into numerous methods and topics covered in biomedical research. In order that you can participate in the workshops you should bring your own lab coat. To be on the safe side you should have a liability insurance which covers damage in the lab.
The list below gives you some information about the workshops that will take place on Friday, November 8th, 2019. Due to limited capacities and overlapping, you are only allowed to participate in one workshop. At the registration you are able to name three preferences of which workshops you would like to join. If workshops are fully booked, we will offer an optional guided city tour for people who did not get a place. Later you will receive specific details about the exact time and location your workshop will take place at. All workshops will end just in time for everyone to join the press-conference on the Marphili simulation at 5 p.m.
IFlickr, Adrian H. Elcock (University of Iowa), PLoS Computational Biology, dx.doi.org/10.1371/journal.pcbi.1000694
Proteinbiochemistry and –spectroscopy
Prof. Dr. Roland Lill, Institute for Cytobiology and Cytopathology, Philipps-University Marburg
Proteins consist of amino acids which form complex macromolecules. In various organs as well as in different cell types, proteins cover numerous and diverse functions. For instance, proteins are involved in maintenance of the cell structure, storing and transport of molecules, signaltransduction, and catalysis of biochemical reactions. In the field of biomedicine, the research on protein-protein interaction is exceptionally important for understanding the functions of proteins which e.g. are involved in metabolic pathways. In this particular workshop you will gain a theoretical as well as a practical insight into different advanced methods currently used in research on protein interactions. Keywords: MicroScale Thermophoresis, Differential Scanning Fluorimetry, Biolayer Interferometry.
Max. 6 participants, Language: German
Molecular Cell Dynamics - Insights From the Fly
Prof. Dr. Sven Bogdan, Institute for Physiology und Pathophysiology (Department of Molecular Cellphysiology), Philipps-University Marburg
Model organisms, such as Drosophila melanogaster, are of keen interest for biomedical research since they are easy accessible for studying principles of developmental and cellular functions. In this workshop you will deal with the fruitfly Drosophila in order to gain insight into working with model organisms in scientific research. For over 100 years, Drosophila has been used in research on pathophysiological mechanisms in neurodegeneration, tumorgenesis, inflammation or metabolic diseases. Furthermore, you will gain a practical insight into Live Cell Microscopy.
Max. 10 participants, Language: German
Biomedical Research: Labour Market and Entry Into the Workforce
Katja Wiechmann und Kristina Textor, Federal Employment Agency Marburg
Studying biomedicine or related degree programmes is not always easy: there is a long educational route with high requirements for the students and also enormous knowledge that has to be gained. In contrast to medical students or engineers, there often is no obvious connection to the job market for biomedical students. In this seminar career officers will talk about hot topics and frequently asked questions regarding entrance into the workforce as a biomedical student.
Questions will include e.g.:
What are my chances at the job market with either bachelor’s or master’s degree as well as a PhD?
Is a PhD always required?
What can I do myself to improve and increase my chances at the job market?
Which different pathways exist for entering into the workforce?
Max. 40 participants, Language: German
Marphili-Simulation – Diagnostics and Risk Management in a fictitious Virus Outbreak-Scenario
Prof. Dr. Andrea Maisner, Institute of Virology, Philipps-University Marburg
A fictitious, realistic scenario will be outlined in the context of this workshop, in which a made-up new virus (Marphili-virus) will reach Germany via returning vacationers. The task of the participants will be to take over the role of a virologist and find answers to the following questions:
Who is currently infected with the new virus, has it already spread, and how dangerous is the infection for the population?
The practical part of this workshop includes examination of blood samples of infected people as well as people who had contact to (possibly) infected patients. After evaluation of the virus diagnostics, a press conference will be held at 5 p.m.
In context of this conference, participants will take over different roles to inform the press and population about the current outbreak while answering critical and provocative questions in a factual manner and without spreading panic.
Max. 24 participants, Language: German
Super Resolution Microscopy
Prof. Dr. Ralf Jacob, Institute for Cytobiology and Cytopathology, Philipps-University Marburg
We invite you to an exciting Microscopy Workshop that covers basic principles as well as super resolution techniques in fluorescence microscopy. Theoretical background will at first be introduced by a 45 min lecture followed by a practical course using two state of the art microscopes. Here, we focus on two techniques in fluorescence light microscopy, live cell and stochastic optical reconstruction microscopy (GSD, STORM). The workshop is organized by the Bioimaging Facility in the Institute of Cytobiology.
Max. 4 participants, Language: German
Molecular Mechanisms of stress replies
Dr. Till Adhikary, Centre for Tumor- and Immunbiology, Philipps-University Marburg
Corticol is the archetype of stress hormones: it reduces and impairs the functions of our immune system, it influences our metabolism and increases the blood pressure. Moreover, corticol seems to promote depression and other psychological disorders. Corticol binds to soluble proteins from the super-family of nuclear receptors which are transcription factors. The glucocorticoid receptor and the mineralocorticoid receptor regulate gene expression. However, the mechanisms of regulation of protein biosynthesis is poorly investigated – especially with regards to repression of gene expression. This seminar will give you an overview on different signals, that lead to release of corticol, feedback control systems and the effect on transcription of specific genes.
CRISPR-mediated epitope tag and point mutation of endogenous proteins for proteomic and epigenetic analysis
Prof. Dr. Alexander Brehm, Centre for Tumor- and Immunbiology, Philipps-University Marburg
Methods of genome editing based on the CRISPR/Cas9-system become of exceeding importance in the field of molecular biological fundamental research. Different CRISPR/Cas9 approaches will be covered in this seminar with regards to epigenetic regulators and mechanisms of gene regulation. For this purpose, epitope tagging of endogenous proteins, arbitrarily induced point mutations, as well as alteration of chromatin structure will be discussed.
Max. 30 participants, Language: German
C. elegans as a model organism
Marina Sinner, Department of Biology, Animal Physiology – AG Neurophysiology
In this workshop, students will learn about the use of Caenorhabditis elegans as a model organism in the context of sleep research. Topics of this hands-on workshop will be the basics of C. elegans-handling, optogenetic tools for C. elegans research and how to use them. This workshop will also focus on the molecular basis of sleep.
Max. 8 participants, Language: German
How to BSL-4
Dr. Olga Dolnik, Institute of Virology, Philipps-University Marburg
What exactly is a BSL-4 lab? And how does it work?
These and many more questions concerning the work under BSL-4 conditions will be answered in this seminar, held by a staff scientist oft the Marburger BSL-4 lab.
Caution: A visit of the BSL-4-laboratory itself is not planned!
Max. 10 participants, Language: German
Dr. Larissa Kolesnikova
It's not normal! Statistics workshop with R.
Dr. Jochen Wilhelm, German Lung Research Center, Justus-Liebig-University Gießen
Most statistical analyses are based on the presumption or premise of normally distributed data.
This workshop is supposed to show that normal distribution is not the normal case and shows, with a concept different from „normal“ statistics-classes, alternative ways for a more general and (hopefully) better comprehension of how to interpret experimental data using statistical models.
Max. 10 participants, Language: German